A quantitative study was conducted to assess the effect of self-instructional module regarding knowledge of digitalis therapy among staff nurses working in a selected hospital at Kollam district. The objectives of the study were to assess the pre-test knowledge regarding digitalis therapy among staff nurses, to evaluate the effect of self-instructional module on knowledge regarding digitalis therapy, to find the association between pre-test knowledge of staff nurses regarding digitalis therapy and the selected demographic variables. Probability simple random sampling technique was used to select 60 staff nurses for the study. The tools used for data collection were demographic data, structured knowledge questionnaire and self-instructional module. The mean post-test knowledge score 47.6 with standard deviation 2.4 was significantly higher than the mean pre-test knowledge 20.6 with standard deviation 5.8. The study showed that there was improvement in the knowledge of staff nurses after implementing self-instructional module and thus self-instructional module was statistically significant at 0.01 level (t=33.83, p<0.00). There was a significant association between pre -test knowledge regarding digitalis therapy and age (x2=1.32, p=0.251). Hence the study suggested that self-instructional module was effective in improving the knowledge of staff nurses regarding digitalis therapy.
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